Carnegie Mellon University
May 24, 2017

Paper Links Overexpression of Sirtuin 6 to Increased Life Span in Mammals

Ziv Bar-Joseph, associate professor of computational biology and machine learning, and graduate student Guy Zinman are among the authors of a paper in the journal Nature that for the first time links overexpression of a gene called sirtuin 6 to increased life span in mammals, specifically mice. Researchers who study aging have been intrigued by the large family of sirtuin genes and their proteins ever since they were linked to longevity in yeast.